Lithium Treatment Could Offer New Option for Traumatic Brain Injury Sufferers

Lithium Treatments for TBI PatientsTraumatic brain injuries (TBI) are one of the leading causes of death and disability in the U.S., according to the Centers for Disease Control and Prevention (CDC). In 2013, there were 2.5 million emergency department visits for TBIs. A study published that same year in the Journal of Occupational and Environmental Medicine named TBIs as one of the most “common, costly, and disabling occupational injuries.” Unfortunately for the millions who suffer this type of injury, treatment options are limited, and much about the brain and its function remains a mystery to doctors and researchers. A recent study from Rutgers University, however, indicates that the use of lithium treatment may provide some effective protection for those who experience a TBI.

What Is a Traumatic Brain Injury?

A traumatic brain injury is defined by the CDC as a bump, blow, or jolt to the head that disrupts the normal function of the brain. A TBI can range in severity from mild to severe and includes such injuries as:

  • Concussion – The most common TBI, a concussion occurs when blood vessels stretch or cranial nerves are damaged inside the brain as the result of an impact or sudden movement.
  • Contusion – A contusion is a bruise or bleeding on the brain.
  • Coup-contrecoup injury – This type of injury occurs when the force of a blow moves the brain across the inside of the skull, where it strikes both at the point of impact and on the opposite side of the head.
  • Second-impact syndrome – Second-impact syndrome is used to describe when a second brain injury is sustained before the symptoms of a previous brain injury have healed.
  • Diffuse axonal injury – This type of injury occurs when shaking or strong rotating of the head cause tearing of nerve tissue in the brain. Car accidents are common causes of diffuse axonal injuries.
  • Penetrating injury – A penetrating injury is the result of the impact from an object forcing hair, skin, bone, or the object itself into the brain.

Common Causes of Work-Related Brain Injuries

Unfortunately, work-related brain injuries are common and occur across all professions—even those that are seemingly safe. The Bureau of Labor Statistics reported more than 91,000 job-related traumatic head injuries in 2015. Some of the common causes of TBIs on the job include:

  • Motor vehicle accidents
  • Falls
  • Struck by or against an object

Complicated Symptoms and Treatments for a TBI

Both diagnosing and treating a TBI can be difficult, as the injuries can present in a wide variety of symptoms. Even those who suffer similar injuries can experience vastly different side effects. In addition, symptoms can continue to appear days, weeks, and even months after the injury. While no two cases are identical, some common symptoms of a TBI include:

  • Headache
  • Nausea and vomiting
  • Fatigue
  • Confusion
  • Memory loss
  • Loss of consciousness
  • Seizures
  • Confusion
  • Mood changes or mood swings

Only a medical professional can determine the extent of a brain injury, based on a physical exam and imaging tests. Even once the injury has been diagnosed, treatment options can also vary. Very mild TBIs may not require any treatment outside a period of rest. For more severe injuries, diuretics, anti-seizure medications, induced coma, and surgery may be necessary. All these options, however, focus on alleviating symptoms and dulling pain.

Lithium May Offer New Options for TBI Victims

To date, little has been discovered to help prevent further damage from occurring in the brain. In many cases, once cells are damaged, they may continue to deteriorate as the chemicals released at the time of the injury build up to toxic levels. Researchers at Rutgers University, though, say they think that the drug lithium may be an effective tool in stopping that dangerous process.

Lithium is a mood stabilizer that affects the flow of sodium through nerve and muscle cells. It is most commonly used to treat bipolar disorder and serious depression. Researchers recently found laboratory evidence that lithium, used in conjunction with the immunosuppressant rapamycin, protects brain cells. According to the study, the drugs stopped the signals of the chemical glutamate between cells and prevented further cell damage and death.

Scientists at Rutgers say future research will examine the efficacy of the combination of lithium and rapamycin in both animals and humans.

If you or someone you love has suffered a TBI while on the job, you may be facing a difficult and uncertain future. Workers’ compensation benefits can help you obtain the medical care and wage replacement your family needs, and the attorneys at Monast Law Office may be able to help. Take a moment to fill out our online contact form, and you will hear back from a member of our team who can answer your questions today.


James Monast
Fighting for Ohio’s Injured Workers and their Families
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